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Rear Osmosis( RO) is a membrane- grounded technology for water desalination. Of consummate significance is the understanding of ion selectivity in fusions of mariners, i.e., to what extent the membrane retains one ion further than another in a multicomponent swab result. The model is grounded on the Donnan steric partitioning severance model extended to include ions of multiple charge countries, similar as bicarbonate/ carbonic acid, ammonia/ ammonium, and hydroxyl/ hydronium ions and the acid – base responses between them and with the membrane charge. By conforming for each ion the rate of ion size over severance size, we can fit the model to the data. We note that the fitted ion sizes don’t always follow a logical order grounded on the ionic or doused size of the ions and that rejection of divalent cations is overrated in some cases. We bandy possible theoretical advancements to address these disagreement. The development of a detailed and validated drugs- grounded model is an important step toward achieving advanced operation and design of RO- grounded desalination systems.